Abnormal mesolimbic control of cortical cholinergic activity has been hypothesized to contribute to the cognitive symptoms of schizophrenia. Stimulation of NMDA receptors in nucleus accumbens (NAC) ...

Nearly four years ago, Steven Paul and coworkers published a provocative paper that showed that a single administration of an anti-Aβ antibody rapidly improved memory in APP-overexpressing mice, ...

An impressive data set that appeared yesterday in Neuron shows that a specific M1 muscarinic receptor agonist can reverse both cognitive deficits as well as the amyloid and tau pathology in the ...