The corticospinal tract (CST) is extensively used as a model system for assessing potential therapies to enhance neuronal regeneration and functional recovery following spinal cord injury (SCI).

After development of diffusion tensor tractography (DTT), which is derived from diffusion tensor imaging (DTI), three-dimensional reconstruction and estimation for three motor tracts, such as the ...

Researchers report that the deletion of the PTEN gene would enhance compensatory sprouting of uninjured CST axons. Furthermore, the deletion up-regulated the activity of another gene, the mammalian ...

Researchers at the Hong Kong University of Science and Technology (HKUST) have found a way to stimulate the growth of axons, which may spell the dawn of a new beginning on chronic SCI treatments.

Binhai Zheng, Jasvinder Atwal, Carole Ho, Lauren Case, Xiao-lin He, K. Christopher Garcia, Oswald Steward, Marc Tessier-Lavigne, Corey S. Goodman Proceedings of the National Academy of Sciences of the ...