本研究系统揭示了DNA双链断裂修复后的一个被长期忽视的层面：染色质结构与基因功能的不可逆改变。这种结构性与功能性损伤可稳定地传递给子代细胞，形成一种可遗传的基因表达缺陷，被作者定义为“染色质疲劳（chromatin ...

Researchers at Duke University used CRISPR technologies to discover previously unannotated stretches of DNA in the ‘dark genome’ that are responsible for controlling how cells sense and respond to the ...

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which ...

A new version of the human reference genome incorporates genetic data from 47 individuals from around the globe, deepening scientists' view into how genes work. When you purchase through links on our ...

Stay up to date on the latest science with Brush Up Summaries. Scientists first aim to design genomes with minimal changes compared to the wild type to minimize the risk of failure. “The native ...

A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies. A "loopy" discovery ...

John Bergeron does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

Researchers from the University of Adelaide's Davies Livestock Research Center (DLRC) have described the most complete cattle ...

The William H. Foege Genome Sciences Building at the University of Washington School of Medicine in Seattle contains laboratories, sequencers, computational facilities, and other resources for ...

The fern Tmesipteris oblanceolata, which scientists just discovered has the longest known genome of any organism. Ferns are known among scientists for having particularly large genomes. Pol Fernandez ...