Strands of DNA wrapped around a histone. Credit: Molekuul/Science Source Histones are among the most abundant proteins in the body. They act as spools that help compact DNA so our enormous genomes ...

Nearly two years into the pandemic, we find ourselves thinking about viruses daily. Amid the dread of hearing about yet another new SARS-CoV-2 variant and longing for normalcy, perhaps you’ve ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

A collaborative effort has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of ...

The biology of histone proteins encompasses their synthesis in the cytosol, nuclear import and incorporation into nucleosomes, as well as subsequent eviction from chromatin, redeposition, storage or ...

There is perhaps no more fundamental property of life than change, both with respect to personal experience and, as the basis of evolution, to the nature of biology itself. The constant genetic ...

What is the histone code? Different chemical marks, such as acetylation, methylation, or phosphorylation, are made to numerous residues on the N-terminal tails of histone proteins. Some posit that ...