A modified pig liver transplanted into a human patient appears to have functioned normally for the duration of the investigation with no signs of rejection. For 10 days, the liver performed its basic ...

Long before a liver tumor appears, a high-fat diet can push liver cells into a risky survival mode. That is the central ...

Of all the organs, the liver is most susceptible to drug toxicity. Drug-induced liver injury (DILI) is a leading cause of drug attrition, with over 750 FDA-approved drugs known to have a level of DILI ...

We’ve reached a new frontier in organ transplantation. In a medical first, scientists announced this week that they successfully kept a genetically modified pig liver functioning inside a human ...

Microfluidic chips that mimic human livers are better at predicting whether a drug is toxic to the liver than conventional animal models used in preclinical experimentations, claims a new study from ...

A potential drug successfully treats the severe form of nonalcoholic fatty liver disease in non-human primates -- bringing scientists one step closer to the first human treatment for the condition ...

Scientists from Cincinnati Children’s Hospital Medical Center and their collaborators have used human stem cells to develop liver organoids that faithfully replicate key zones observed in human livers ...

What happens when people unknowingly eat, drink or inhale nearly invisible pieces of plastic? Although it's unclear what impact this really has on humans, researchers have now taken a step toward ...

On a recent Thursday afternoon, researchers Lanuza Faccioli and Zhiping Hu wheeled an inconspicuous black and white plastic cooler from an operating room at a hospital in downtown Pittsburgh. Inside ...

Chinese researchers are reporting new steps in the quest for animal-to-human organ transplants – with a successful pig kidney transplant and a hint Wednesday that pig livers might eventually be useful ...