The mevalonate pathway is central to the biosynthesis of isoprenoids and sterols, underpinning a range of essential cellular processes. Farnesyl diphosphate synthase (FPPS) is a pivotal enzyme in this ...

Masashi Suzuki, Shoko Nakagawa, Yukiko Kamide, Keiko Kobayashi, Kiyoshi Ohyama, Hiromi Hashinokuchi, Reiko Kiuchi, Kazuki Saito, Toshiya Muranaka, Noriko Nagata Journal of Experimental Botany, Vol. 60 ...

The earty morphogenetic mechanisms involved in heart formation are evolutionarily conserved. A screen for genes that control Drosophila heart development revealed a cardiac defect in which pericardial ...

Among 312,907 identified patients with cancer, treatment groups included statin users (n = 65,440), nonstatin users who received medications that block cholesterol absorption (n = 9,289), and nonusers ...

Researchers showed that the mevalonate pathway is essential for embryonic development by promoting primitive streak formation, a key landmark for establishing embryo symmetry and gastrulation. The ...

Creative Proteomics, a leading provider of proteomics and metabolomics services, today announced the launch of its advanced Mevalonate Pathway Analysis service. This innovative offering is designed to ...

Increased risk of MDS/AML post radiation treatment for breast cancer: Analysis of SEER data 2001-2008. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I. This abstract does not ...

Schematic diagram of mouse embryonic development on the indicated days. Bottom: The mevalonate pathway produces farnesyl diphosphate for cholesterol synthesis, protein geranylgeranylation and protein ...

Artemisia annua is celebrated for its production of artemisinin, a powerful antimalarial agent. Although its glandular secretory trichomes have been the focus of extensive research, a complete ...