Monoclonal gammopathy of undetermined significance (MGUS) is one of the most common premalignant plasma cell disorders. It is a precursor for multiple myeloma and other related malignancies. Patients ...

We hypothesized that the suppression of uninvolved immunoglobulin in monoclonal gammopathy of undetermined significance (MGUS) as detected by suppression of the isotype-specific heavy and light chain ...

Computer-Assisted Flagging of Individuals at High Risk of Colorectal Cancer in a Large Health Maintenance Organization Using the ColonFlag Test Recent advances have uncovered therapeutic interventions ...

A new research perspective was published in Oncotarget's Volume 15 on January 16, 2024, entitled, “Bone marrow adipocytes provide early sign for progression from MGUS to multiple myeloma.” Multiple ...

Individuals with low-risk or intermediate-risk monoclonal gammopathy of undetermined significance (MGUS) may convert to high-risk MGUS and progress to multiple myeloma within 5 years, researchers ...

Patients with multiple myeloma (MM) appear to have better survival if they are found to have monoclonal gammopathy of undetermined significance (MGUS) first, the state that precedes MM and which is ...

Risk of progression to multiple myeloma is higher in obese patients with monoclonal gammopathy of unknown significance (MGUS), compared to normal weight persons. Monoclonal gammopathy of unknown ...

New research shows that excess weight increases the risk that a benign blood disorder will progress into multiple myeloma, a cancer of the blood. The study, by a team at Washington University School ...

Researchers have been trying to find a way to screen populations at high risk of developing a precursor condition to multiple myeloma in order to intervene early and reduce disease prevalence and ...

We developed precompiled lexicons and classification rules as features for the following ML classifiers: logistic regression, random forest, and support vector machines (SVMs). These features were ...

A monoclonal gammopathy of undetermined significance (MGUS) occurs in up to 2 percent of persons 50 years of age or older. Reliable predictors of progression have not been identified, and information ...

An abnormal protein found in the blood – called monoclonal gammopathy of undetermined significance (MGUS) – may lead to multiple myeloma progression, even after 30 years of disease stability, ...