Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, No. 24 (Jun. 15, 2004), pp. 8924-8929 (6 pages) Vaccinia virus complement control protein (VCP), a homolog of ...

Heparan-sulphate glycosaminoglycans (HSGAGs) act at the cell–extracellular-matrix (ECM) interface to modulate cell signalling, thereby regulating how a cell perceives its environment. HSGAGs interact ...

We have fractionated crude porcine heparin to obtain highly active as well as relatively inactive species of molecular weight ≈ 7000 with specific anticoagulant activities of 360 and 12 units/mg, ...

A potential treatment for a serious clotting condition that can strike patients who receive heparin to treat or prevent blood clots may lie within reach by elucidating the structure of the protein ...

If commercialization works out, the findings could extend the market reach of ultralow molecular weight heparin, as this form is called. And the chemoenzymatic synthesis that the researchers described ...

Scientists have explained how contaminated batches of the blood-thinner heparin were able to slip past traditional safety screens and kill dozens of patients recently in the United States and Germany.

DURHAM, N.C. -- Researchers at Duke Medicine have identified a new strategy for treating neuroblastoma using a modified version of heparin, a century-old injectable drug that thins the blood to ...