Synonymous mutations have long been ignored in cancer studies since they don’t affect the amino acid sequences of proteins. But research increasingly reveals that they can have disease-driving effects ...

A central assumption about so-called synonymous mutations, which are changes in the coding sequence of proteins that do not lead to changes in its amino acid sequence, is being questioned by a study ...

Genetic disorders — like cystic fibrosis and Huntington’s disease — are considered incurable, with gene mutations occurring in essentially every cell of the body. Gene mutations occur when one ...

For decades, researchers have viewed synonymous mutations as inconsequential quirks of the genome. Due to the way the genetic code is set up—where multiple three-base-pair codons can encode the same ...

A team of scientists from Portugal has recently estimated the rate of mutation in two circulating variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using experimental evolution ...