A research team from the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine at the University of ...
A research team from the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine at the University of Hong Kong (HKUMed) has ...
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G-Protein Coupled Receptors (GPCRs) Market Size to Hit USD 6.04 Billion by 2032, Growing at ...
Global g-protein coupled receptors (GPCRs) market growth is Driven by Rising drug discovery activities, expanding applications in targeted therapeutics, and increasing prevalence of chronic and ...
The 8-Bromo-cAMP sodium salt PKA activator, a synthetic analog of cAMP, is one of the most potent tools of investigating and playing with this pathway, which has become an essential part of ...
Gyre Pharmaceuticals completed a Pre-NDA meeting with China’s CDE, which agreed that the existing Phase 3 clinical data support a conditional ...
一点资讯 on MSN
Timp1基因功能与研究突破：从伤口愈合到抗衰老的神奇操作
不小心蹭破膝盖，有人恢复迅速，有人却久不愈合？中老年人常犯的膝盖疼，或许不只是“年纪大”那么简单。在细胞层面，Timp1基因就像一位“全能修复师”——既能加速伤口愈合、守护组织健康，近年还展现出抗衰与神经修复的潜力。本文将聚焦Timp1的核心功能与研 ...
*仅供医学专业人士阅读参考高级别浆液性卵巢癌（HGSC）是导致绝大多数卵巢癌相关死亡的主要原因，其中约50%的病例存在同源重组修复缺陷，导致对铂类化疗和PARP抑制剂敏感。然而，相当一部分肿瘤，特别是CCNE1扩增或同源重组功能正常的肿瘤，对现有疗法 ...
在癌症的庞大王国中，胰腺导管腺癌（PDAC）堪称“癌王”。它发病隐匿，进展迅猛，五年生存率长期徘徊在惨淡的13%。当大多数癌症的疗效因精准医疗而节节攀升时，胰腺癌的防治战局却始终严峻。近日，国际知名期刊《信号转导与靶向治疗》（Signal ...
癌症治疗领域长期以来面临着一个严峻挑战：许多肿瘤细胞对传统化疗和靶向治疗产生耐药性，尤其是那些凋亡信号通路存在缺陷的恶性肿瘤。这一困境促使科学家将目光转向一种新型细胞死亡方式——铁死亡（ferroptosis）。铁死亡是由铁依赖性的脂质过氧化累积引发的调节性细胞死亡，其独特机制为克服肿瘤耐药性提供了新思路。近期，《Nature》杂志背靠背发表的两项重磅研究，通过揭示铁死亡抑制因子FSP1（ferr ...
Burkitt's lymphoma is a rare and aggressive blood cancer characterized by a translocation of the MYC gene. It occurs most ...
Background Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality with limited therapeutic options. Despite ...
研究团队提出的关键切入点在于：交感神经过度兴奋是2型糖尿病高血糖症状的重要驱动因素之一，会促进肝脏糖异生、抑制胰岛素分泌，进而加重高血糖及相关并发症。EDN通过消融支配肝脏、胰腺、胃肠道等内脏器官的交感神经，尝试从“上游调控”层面改善代谢状态 。
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