I discuss spinal muscular atrophy (SMA), a devastating neuromuscular genetic disease that can be detected through newborn screening. We talk about the warning signs of SMA type one—including floppy baby syndrome, difficulty holding up the head, frog-like positioning, rapid belly breathing, feeding difficulties, and delayed motor milestones. I explain that while SMA type one is fatal by age two if untreated, early detection through a simple heel prick test and disease-modifying therapy can allow